Exogenous ketones, HDACi, and cancer

Steve Kirsch Uncategorized

I have Waldenstrom’s Macroglobulinemia, a fatal blood cancer that I’ve controlled with an HDAC inhibitor known as LBH-589 (Panobinostat trade name Farydak). There is evidence to suggest that people can get a similar HDAC-i effect with ketones. The idea is to keep ketones at > 1mM at least 12hr/day. You can do this two ways: 1) eating a ketogenic diet …